Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 13/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21736635 | 0.85 | KLKB1 (0.45) | KLKB1ALKBH1RBP4POLBSMN1; SMN2 | |
| SCHEMBL21736872 | 0.82 | KLKB1 (0.47) | KLKB1ALKBH1RBP4 | |
| SCHEMBL21736873 | 0.82 | KLKB1 (0.36) | KLKB1ALKBH1RBP4POLBSMN1; SMN2 | |
| SCHEMBL21736621 | 0.75 | KLKB1 (0.45) | KLKB1 | |
| SCHEMBL21736738 | 0.75 | KLKB1 (0.49) | KLKB1RBP4 | |
| SCHEMBL24918413 | 0.74 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL24918819 | 0.74 | KLKB1 (0.48) | KLKB1 | |
| SCHEMBL21736732 | 0.71 | KLKB1 (0.40) | KLKB1POLBSMN1; SMN2 | |
| SCHEMBL21736620 | 0.71 | KLKB1 (0.47) | KLKB1RBP4 | |
| SCHEMBL21736879 | 0.71 | KLKB1 (0.46) | KLKB1ALKBH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3863713-B1 | PHENYLTETRAZOLE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2023-01-25 | — | — | EP | disclosed |