Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24919875 | 0.77 | SNCA (0.51) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL24919880 | 0.75 | KDM4E (0.51) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL31069467 | 0.75 | KDM4E (0.51) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL15011554 | 0.75 | SMPD3 (0.50) | SNCA | |
| SCHEMBL31083140 | 0.74 | SNCA (0.37) | LMNAGAAMAPTSNCA | |
| SCHEMBL24920104 | 0.74 | KDM4E (0.50) | KDM4EMEN1ALDH1A1LMNAGAA | |
| SCHEMBL257903 | 0.72 | MAOB (0.47) | MEN1GAAMAPTKMT2A | |
| SCHEMBL29458129 | 0.72 | HTT (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL25384525 | 0.72 | HTT (0.46) | KDM4EMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL26050415 | 0.71 | EGFR (0.43) | KDM4EMEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023004138-A1 | AGONISTS OF TYRO3 AS PROTECTION AGAINST PODOCYTE INJURY IN KIDNEY GLOMERULAR DISEASE | DAS BHASKAR (US) | 2023-01-26 | — | — | WO | disclosed |