Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | FDPS | P14324 | 3/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.35 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24391728 | 0.82 | TP53 (0.42) | TP53 | |
| SCHEMBL19776012 | 0.81 | TP53 (0.41) | TP53GPR84FDPSFFAR1FAAH | |
| SCHEMBL25519858 | 0.77 | EPHX1 (0.41) | TP53FDPSFAAHMAPT | |
| Sulfuric Acid SCHEMBL19811275 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19812222 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19811993 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19811663 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19811354 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19811181 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA | |
| Sulfuric Acid SCHEMBL19811838 | 0.75 | TP53 (0.53) | TP53GPR84FDPSFFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024302-A1 | 2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS | ARCUS BIOSCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230024302-A1 | 2,3,5-TRISUBSTITUTED PYRAZOLO[1,5-A]PYRIMIDINE COMPOUNDS | PIK3CA, PIK3CG, PIK3CD | TP53 147/4885GPR84 1684/4885FDPS 1034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.