SCHEMBL24920792

SCHEMBL24920792

COCC1(NCC(C)=O)CCCC1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 12/20 0.54
NPSR1 Q6W5P4 1/20 0.32
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
MGAM2 Q2M2H8 1/20 0.31
CYP4F2 P78329 1/20 0.31
CYP4A11 Q02928 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24920874 0.96 DPP4 (0.50) DPP4MGAMGAASIMGAM2
SCHEMBL25857225 0.77 DPP4 (0.36) DPP4
SCHEMBL15631692 0.76 MGAM (0.39) DPP4MGAMGAASIMGAM2
SCHEMBL24920824 0.76 DPP4 (0.41) DPP4NPSR1CYP4F2CYP4A11
SCHEMBL16176095 0.73 DPP4 (0.42) DPP4NPSR1CYP4F2CYP4A11
SCHEMBL24920700 0.72 DPP4 (0.41) DPP4
SCHEMBL6514999 0.71 DPP4 (1.00) DPP4
SCHEMBL25857135 0.70 DPP4 (0.32) DPP4
SCHEMBL24554762 0.69 DPP4 (0.37) DPP4
SCHEMBL22826703 0.68 DPP4 (0.35) DPP4MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023006097-A1 BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER 海创药业股份有限公司 2023-02-02 WO disclosed