Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 19/20 | 0.56 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.46 |
| ▸ | IL1B | P01584 | 1/20 | 0.46 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.46 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19585179 | 0.85 | CRBN (0.56) | CRBNBRD4TNFIL1BIKZF1 | |
| SCHEMBL22566231 | 0.80 | CRBN (0.55) | CRBNIKZF2 | |
| SCHEMBL22566224 | 0.80 | CRBN (0.47) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL22566228 | 0.80 | IKZF2 (0.57) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL24294391 | 0.80 | IKZF2 (0.57) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL24294325 | 0.80 | IKZF2 (0.57) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL20128642 | 0.79 | CRBN (0.57) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL20128661 | 0.79 | CRBN (0.64) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL22566238 | 0.78 | CRBN (0.47) | CRBNIKZF2BRD4TNFIL1B | |
| SCHEMBL19585852 | 0.77 | IKZF2 (0.48) | CRBNIKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |