Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | BTK | Q06187 | 3/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30212506 | 1.00 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19BTK | |
| SCHEMBL30988311 | 1.00 | KMT2A (0.39) | KMT2AMEN1CYP1A2CYP2C19BTK | |
| SCHEMBL27233970 | 0.91 | KMT2A (0.40) | KMT2AMEN1CYP1A2CYP2C19FAAH | |
| SCHEMBL27233975 | 0.91 | KMT2A (0.40) | KMT2AMEN1CYP1A2CYP2C19FAAH | |
| SCHEMBL24921783 | 0.83 | PIK3CD (0.40) | KMT2ABTKPIK3CDCKS1BSKP1 | |
| SCHEMBL30212383 | 0.83 | PIK3CD (0.40) | KMT2ABTKPIK3CDCKS1BSKP1 | |
| SCHEMBL27233916 | 0.82 | CHRNA7 (0.39) | KMT2AMEN1CYP1A2CYP2C19FAAH | |
| SCHEMBL27233918 | 0.82 | CHRNA7 (0.39) | KMT2AMEN1CYP1A2CYP2C19FAAH | |
| SCHEMBL24922679 | 0.81 | BTK (0.42) | KMT2ABTKPIK3CDCKS1BSKP1 | |
| SCHEMBL24922304 | 0.81 | BTK (0.42) | KMT2ABTKPIK3CDCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006097-A1 | BIFUNCTIONAL CHIMERIC HETEROCYCLIC COMPOUND AND USE THEREOF AS ANDROGEN RECEPTOR DEGRADER | 海创药业股份有限公司 | 2023-02-02 | — | — | WO | disclosed |