SCHEMBL2492222

SCHEMBL2492222

CCC(C(=O)O)n1c2c(c3cc(F)ccc31)CC(N(CCc1ccccc1F)C(C)=O)CC2

nearest known ligand 0.45

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 19/20 0.45
HTR6 P50406 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2492221 1.00 PTGDR2 (0.45) PTGDR2HTR6
SCHEMBL1899238 0.91 PTGDR2 (0.47) PTGDR2HTR6
SCHEMBL1899234 0.91 PTGDR2 (0.47) PTGDR2HTR6
SCHEMBL2489507 0.88 PTGDR2 (0.44) PTGDR2HTR6
SCHEMBL1905043 0.88 PTGDR2 (0.46) PTGDR2HTR6
SCHEMBL2489509 0.88 PTGDR2 (0.44) PTGDR2HTR6
SCHEMBL1905048 0.88 PTGDR2 (0.46) PTGDR2HTR6
SCHEMBL1903221 0.86 PTGDR2 (0.47) PTGDR2HTR6
SCHEMBL1903222 0.86 PTGDR2 (0.47) PTGDR2HTR6
SCHEMBL1901324 0.85 PTGDR2 (0.44) PTGDR2HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2051962-B1 (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES ACTELION PHARMACEUTICALS LTD (CH) 2011-10-26 EP disclosed