Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | SHBG | P04278 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070691 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL671850 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL21656667 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL5700121 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL672135 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL670619 | 1.00 | EPHX1 (0.59) | EPHX1TP53KDM4EGMNNLMNA | |
| Hydrochloric Acid SCHEMBL8201526 | 0.97 | EPHX1 (0.56) | EPHX1TP53KDM4EGMNNLMNA | |
| SCHEMBL4609721 | 0.97 | — | — | |
| SCHEMBL15531073 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL30866173 | 0.89 | KDM4E (0.46) | EPHX1TP53KDM4EGMNNLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2379491-A1 | PROCESS FOR SYNTHESIS OF AMINO-METHYL TETRALINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2011-10-26 | — | — | EP | disclosed |
| WO-2010069778-A1 | PROCESS FOR SYNTHESIS OF AMINO-METHYL TETRALINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-24 | — | — | WO | disclosed |