Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1752706 | 0.89 | CYP2C19 (0.74) | CYP2C19KCNH2 | |
| SCHEMBL15259272 | 0.89 | CYP2C19 (0.71) | CYP2C19KCNH2 | |
| SCHEMBL2488290 | 0.88 | CYP2C19 (0.67) | CYP2C19KCNH2 | |
| SCHEMBL15253728 | 0.87 | CYP2C19 (0.69) | CYP2C19KCNH2 | |
| SCHEMBL20357794 | 0.87 | CYP2C19 (0.66) | CYP2C19KCNH2 | |
| SCHEMBL15259271 | 0.86 | CYP2C19 (0.68) | CYP2C19KCNH2 | |
| Hydrochloric Acid SCHEMBL18091089 | 0.86 | CYP2C19 (0.68) | CYP2C19KCNH2 | |
| SCHEMBL15254190 | 0.86 | CYP2C19 (0.68) | CYP2C19KCNH2 | |
| SCHEMBL15254127 | 0.86 | CYP2C19 (0.65) | CYP2C19KCNH2 | |
| SCHEMBL15259270 | 0.86 | CYP2C19 (0.70) | CYP2C19KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011132070-A1 | PROCESS FOR THE PREPARATION OF 2-AMINO-SUBSTITUTED 1,3-BENZOTHIAZINE-4-ONES | MAKAROV VADIM A (RU) | 2011-10-27 | — | — | WO | disclosed |
| EP-2380886-A1 | Process for the preparation of 2-aminosubstituted 1,3-benzothiazine-4-ones | Makarov Vadim A. (RU) | 2011-10-26 | — | — | EP | disclosed |