Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | SLC6A15 | Q9H2J7 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23058960 | 0.86 | MAPK14 (0.58) | MAPK14SRD5A1SRD5A2 | |
| SCHEMBL1918550 | 0.82 | MAPT (0.58) | MAPK14MAPTSRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL23059138 | 0.81 | MAPK14 (0.47) | MAPK14MAPTALDH1A1NPC1TSHR | |
| SCHEMBL11684948 | 0.80 | SRD5A1 (0.72) | MAPK14SRD5A1SRD5A2NR1H4 | |
| SCHEMBL30583381 | 0.79 | BRD4 (0.55) | MAPK14MAPTSRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL31337617 | 0.79 | BRD4 (0.55) | MAPK14MAPTSRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL26124045 | 0.79 | MAPK14 (0.63) | MAPK14 | |
| SCHEMBL10443684 | 0.78 | CA12 (0.57) | MAPK14MAPTSRD5A1SRD5A2ALDH1A1 | |
| SCHEMBL5846673 | 0.77 | MAPT (0.68) | MAPTALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4179934 | 0.76 | SRD5A1 (0.55) | MAPK14MAPTSRD5A1SRD5A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | SYNOVO GMBH (DE) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017312-A1 | CENTRALLY ACTIVE P38ALPHA INHIBITING COMPOUNDS | MAPK1, MAPK8, MAPK7 | MAPK14 10/4885MAPT 880/4885SRD5A1 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.