SCHEMBL24928201

SCHEMBL24928201

Cc1cc(I)c(Cl)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CD44 P16070 1/20 0.46
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
CYP3A4 P08684 3/20 0.37
LMNA P02545 1/20 0.37
S1PR1 P21453 1/20 0.32
HTT P42858 1/20 0.31
CHRM1 P11229 1/20 0.31
ALOX15 P16050 1/20 0.31
MAOA P21397 1/20 0.31
TBXA2R P21731 1/20 0.31
ADRA1A P35348 1/20 0.31
HTR2B P41595 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14162640 0.89 CD44 (0.46) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL21856930 0.86 CD44 (0.36) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL17752359 0.83 CD44 (0.46) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL8261003 0.78 CD44 (0.58) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL9974977 0.78 CYP3A4 (0.41) CYP3A4ALDH1A1GAAMAPK1AHR
SCHEMBL19931888 0.78 CD44 (0.46) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL832773 0.77 CD44 (0.41) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL30384504 0.77 AHR (0.34) CD44S1PR1AHR
SCHEMBL10306205 0.77 CD44 (0.41) CD44GRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL404666 0.77 CD44 (0.65) CD44GRIN2DGRIN3BGRIN1GRIN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023008644-A1 ORGANIC COMPOUND, AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME (주)피엔에이치테크 2023-02-02 WO disclosed