⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2492963 | 0.61 | — | — | |
| SCHEMBL12522928 | 0.58 | — | — | |
| SCHEMBL8959112 | 0.58 | — | — | |
| SCHEMBL910100 | 0.58 | — | — | |
| SCHEMBL3915816 | 0.56 | — | — | |
| SCHEMBL11683651 | 0.56 | — | — | |
| SCHEMBL10867699 | 0.56 | — | — | |
| SCHEMBL14424417 | 0.56 | — | — | |
| SCHEMBL8723351 | 0.56 | — | — | |
| SCHEMBL10867704 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380898-B1 | Process to make glucocorticoid compounds | GLAXO GROUP LTD (GB) | 2013-08-28 | — | — | EP | disclosed |
| EP-1644398-B1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LTD (GB) | 2013-01-09 | — | — | EP | disclosed |
| EP-2380898-A1 | Process to make glucocortisoid compounds | GLAXO GROUP LIMITED (GB) | 2011-10-26 | — | — | EP | disclosed |
| US-20100152148-A1 | NOVEL COMPOUNDS | BIGGADIKE KEITH | 2010-06-17 | — | — | US | disclosed |
| US-7638508-B2 | Glucocorticosteroid compound having anti-inflammatory activity | GLAXO GROUP LIMITED (GB) | 2009-12-29 | — | — | US | disclosed |
| US-7524970-B2 | Compounds | GLAXO GROUP LIMITED (GB) | 2009-04-28 | — | — | US | disclosed |
| US-20080070880-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI-INFLAMMATORY ACTIVITY | BIGGADIKE KEITH | 2008-03-20 | — | — | US | disclosed |
| US-20080021231-A1 | Novel compounds | BIGGADIKE KEITH | 2008-01-24 | — | — | US | disclosed |
| US-20080015360-A1 | Novel compounds | JOHN MATTHEW P | 2008-01-17 | — | — | US | disclosed |
| US-7288536-B2 | Specific glucocorticosteroid compound having anti-inflammatory activity | GLAXO GROUP LIMITED (GB) | 2007-10-30 | — | — | US | disclosed |
| US-20060247219-A1 | Specific glucocorticosteriod compound having anti-inflamatory activity | GLAXO GROUP LIMITED (GB) | 2006-11-02 | — | — | US | disclosed |
| EP-1644398-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005005451-A1 | SPECIFIC GLUCOCORTICOSTEROID COMPOUND HAVING ANTI- INFLAMMATORY ACTIVITY | GLAXO GROUP LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |