⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10283706 | 0.73 | — | — | |
| SCHEMBL18612533 | 0.69 | — | — | |
| SCHEMBL20616337 | 0.69 | — | — | |
| SCHEMBL21767297 | 0.69 | — | — | |
| SCHEMBL22916885 | 0.67 | TSHR (0.30) | — | |
| SCHEMBL19122907 | 0.67 | — | — | |
| SCHEMBL13924814 | 0.65 | — | — | |
| SCHEMBL18597021 | 0.65 | — | — | |
| SCHEMBL20673797 | 0.65 | — | — | |
| SCHEMBL18653078 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023250439-A1 | TREX1 INHIBITORS AND USES THEREOF | TEMPEST THERAPEUTICS, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023215740-A1 | IMMUNOMODULATORY ANTIBODY-DRUG CONJUGATES | SEAGEN INC. (US) | 2023-11-09 | — | — | WO | disclosed |
| WO-2023004266-A1 | IMMUNOCONJUGATES AND METHODS | RECURIUM IP HOLDINGS, LLC (US) | 2023-01-26 | — | — | WO | disclosed |