Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30240807 | 1.00 | MAOB (0.46) | MAOBFFAR1PARP15RAB9ASMN1; SMN2 | |
| SCHEMBL24933637 | 0.90 | MAOB (0.44) | MAOBFFAR1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30240765 | 0.89 | MAOB (0.47) | MAOBFFAR1PARP15MRGPRX4PARP10 | |
| SCHEMBL24932976 | 0.89 | MAOB (0.52) | MAOBPARP15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL30240782 | 0.89 | MAOB (0.52) | MAOBPARP15RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL24933615 | 0.89 | MAOB (0.60) | MAOBFFAR1MAOAMRGPRX4 | |
| SCHEMBL24933362 | 0.89 | MAOB (0.47) | MAOBFFAR1PARP15MRGPRX4PARP10 | |
| SCHEMBL24933349 | 0.88 | GSTP1 (0.50) | MAOBFFAR1PARP10 | |
| SCHEMBL24932968 | 0.87 | GRM2 (0.40) | MAOBFFAR1ALDH1A1 | |
| SCHEMBL30240665 | 0.87 | GRM2 (0.40) | MAOBFFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| CN-117980292-A | Substituted pyridone compounds for the treatment of orthomyxoviral infections | 诺华股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| WO-2023002443-A1 | SUBSTITUTED PYRIDONE COMPOUNDS USEFUL TO TREAT ORTHOMYXOVIRUS INFECTIONS | NOVARTIS AG (CH) | 2023-01-26 | — | — | WO | disclosed |