Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 4/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20143627 | 1.00 | CA1 (0.52) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL28520590 | 0.92 | — | — | |
| SCHEMBL31322932 | 0.81 | CA1 (0.48) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL101401 | 0.79 | CA1 (0.56) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL27863219 | 0.78 | CA1 (0.50) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL5711695 | 0.78 | CA1 (0.45) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL20520253 | 0.77 | CA1 (0.54) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL2301401 | 0.77 | CA1 (0.54) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL20520239 | 0.77 | CA1 (0.54) | CA1OPRM1FDPSACE2SPHK1 | |
| SCHEMBL20520255 | 0.77 | CA1 (0.54) | CA1OPRM1FDPSACE2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020092-A1 | COMPOSITIONS FOR DELIVERY OF ANTISENSE COMPOUNDS | ENTRADA THERAPEUTICS, INC. | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230020092-A1 | COMPOSITIONS FOR DELIVERY OF ANTISENSE COMPOUNDS | HNRNPAB, SNRPE, HNRNPA2B1 | CA1 4679/4885OPRM1 3732/4885FDPS 3868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.