SCHEMBL2493539

SCHEMBL2493539

[O-][S+](c1ccccc1)c1ccc2nnnn2n1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
TP53 P04637 1/20 0.46
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
HSD17B10 Q99714 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.40
HTT P42858 1/20 0.39
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3986769 0.63 HTT (0.49) MAPTMEN1ALDH1A1TP53CYP1A2
SCHEMBL11852029 0.61 HTT (0.63) MAPTMEN1ALDH1A1TP53CYP1A2
(Phenylsulfinyl)Benzene SCHEMBL43199 0.61 TDP1 (0.37) MAPTALDH1A1HPGDTSHRHSD17B10
(Phenylsulfinyl)Benzene SCHEMBL29572063 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
SCHEMBL12336893 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
(Phenylsulfinyl)Benzene SCHEMBL11455732 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
(Phenylsulfinyl)Benzene SCHEMBL30226308 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
(Phenylsulfinyl)Benzene SCHEMBL11889252 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
(Phenylsulfinyl)Benzene SCHEMBL29381213 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1
(Phenylsulfinyl)Benzene SCHEMBL29227233 0.59 TDP1 (0.35) ALDH1A1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4313144-A1 COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME Angiex, Inc. (US) 2024-02-07 EP claimed
CN-117355333-A Combination comprising anti-TM 4SF1 antibody and immunotherapeutic agent and method of use thereof 安吉克公司 2024-01-05 CN claimed
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME ANGIEX, INC. 2023-09-21 US claimed
WO-2022204565-A1 COMBINATIONS COMPRISING ANTI-TM4SF1 ANTIBODIES AND IMMUNOTHERAPEUTIC AGENTS AND METHODS OF USING THE SAME ANGIEX, INC. (US) 2022-09-29 WO claimed
EP-4011367-A1 COMPOUNDS FOR USE IN THE TREATMENT OF COVID-19 Dompe' Farmaceutici S.P.A. (IT) 2022-06-15 EP claimed
WO-2016160880-A1 METHODS AND COMPOSITIONS FOR TREATING PANCREATITIS BAYLOR RESEARCH INSTITUTE (US) 2016-10-06 WO claimed
EP-4709405-A2 FLUORESCEIN-LABELED NERVE TARGETING PEPTIDE FORMULATIONS AND RELATED METHODS Alume Biosciences, Inc. (US) 2026-03-18 EP disclosed
EP-4705765-A2 BUCCAL CELL DIAGNOSIS OF RISK IN FAMILIAL ARRHYTHMIA SYNDROMES Beth Israel Deaconess Medical Center, Inc. (US) 2026-03-11 EP disclosed
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery ALUME BIOSCIENCES, INC. (US) 2026-01-27 US disclosed
US-20250381165-A1 Method of Use for Benzofuran Compounds TAMPA BAY RESEARCH INSTITUTE, INC. (US) 2025-12-18 US disclosed
US-20250352473-A1 NANOLIPOSOME COMPOSITIONS AND METHODS OF USING THE SAME US GOV VETERANS AFFAIRS (US) 2025-11-20 US disclosed
US-12383500-B2 Nanoliposome compositions and methods of using the same THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) 2025-08-12 US disclosed
US-20250041408-A1 SMALL MOLECULE IMMUNOPOTENTIATOR CONJUGATES OF NFKB ACTIVATORS AS ADJUVANTS WITH ENHANCED EFFICACY AND REDUCED TOXICITY THE UNIVERSITY OF CHICAGO 2025-02-06 US disclosed
US-11299515-B2 Optimized peptides for targeting human nerves and their use in image guided surgery, diagnostics and therapeutic THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-04-12 US disclosed
US-11246940-B2 Peptides whose uptake in cells is controllable THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-02-15 US disclosed
WO-2016160880-A1 METHODS AND COMPOSITIONS FOR TREATING PANCREATITIS BAYLOR RESEARCH INSTITUTE (US) 2016-10-06 WO disclosed
US-8330039-B2 Solar cell modules with poly(vinyl butyral) encapsulant comprising unsaturated heterocyclic compound E I DU PONT DE NEMOURS AND COMPANY (US) 2012-12-11 US disclosed
EP-2380208-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. du Pont de Nemours and Company (US) 2011-10-26 EP disclosed
WO-2010085664-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-29 WO disclosed
US-20100180947-A1 SOLAR CELL MODULES WITH POLY(VINYL BUTYRAL) ENCAPSULANT COMPRISING UNSATURATED HETEROCYCLIC COMPOUND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-07-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12533425-B2 Methods and systems using peptides for targeting and mapping human nerves in image guided surgery, diagnostics and therapeutic delivery NGLY1, VGF, GAP43 MAPT 832/4885MEN1 1105/4885ALDH1A1 4784/4885
US-20250041408-A1 SMALL MOLECULE IMMUNOPOTENTIATOR CONJUGATES OF NFKB ACTIVATORS AS ADJUVANTS WITH ENHANCED EFFICACY AND REDUCED TOXICITY NFKBIA, NFRKB, NFKB2 MAPT 3316/4885MEN1 4363/4885ALDH1A1 4393/4885
US-20250381165-A1 Method of Use for Benzofuran Compounds CD74, TAP1, TAP2 MAPT 2893/4885MEN1 4485/4885ALDH1A1 3262/4885
US-20230293713-A1 ANTI-TM4SF1 ANTIBODY DRUG CONJUGATES AND METHODS OF USING SAME TM9SF4, TM9SF2, TM9SF3 MAPT 2576/4885MEN1 2103/4885ALDH1A1 2644/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.