SCHEMBL24936243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29632362	1.00	CHEK1 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	SCHEMBL24935546	0.91	KCNH2 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	SCHEMBL29632320	0.91	KCNH2 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	Prexasertib SCHEMBL30528862	0.90	CHEK1 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	SCHEMBL19208017	0.90	CHEK1 (0.81)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	Prexasertib SCHEMBL30517001	0.90	CHEK1 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	Prexasertib SCHEMBL29371799	0.90	CHEK1 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	SCHEMBL23327317	0.90	CHEK1 (0.81)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	Prexasertib SCHEMBL1975451	0.90	CHEK1 (1.00)	CHEK1KCNH2NUAK1CHEK2RPS6KB1
	SCHEMBL19208028	0.90	CHEK1 (0.81)	CHEK1KCNH2NUAK1CHEK2RPS6KB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.