Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24434622 | 0.87 | SMN1; SMN2 (0.43) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24435068 | 0.84 | CNR2 (0.41) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434682 | 0.83 | SMN1; SMN2 (0.46) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24435120 | 0.83 | AOC3 (0.45) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434602 | 0.83 | CNR2 (0.41) | NPC1RAB9ASCN3ASMN1; SMN2POLB | |
| SCHEMBL24434817 | 0.82 | SCD (0.47) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434744 | 0.82 | CSNK2A1 (0.47) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434536 | 0.82 | SCN3A (0.48) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434786 | 0.82 | ADORA1 (0.47) | NPC1RAB9ALMNAHTTMEN1 | |
| SCHEMBL24434913 | 0.81 | SMN1; SMN2 (0.43) | NPC1RAB9ALMNAHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010051-A1 | PROTEIN SECRETION INHIBITORS | GATE BIOSCIENCE, INC. (US) | 2023-02-02 | — | — | WO | disclosed |