SCHEMBL24938226

SCHEMBL24938226

CCC(O)NC1CCC(=O)NC1=O

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 20/20 0.43
▸ DDB1 Q16531 13/20 0.43
▸ IKZF3 Q9UKT9 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23799091 0.82 CRBN (0.44) CRBNDDB1IKZF3
SCHEMBL21214936 0.81 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL23551779 0.78 CRBN (0.49) CRBNDDB1IKZF3
SCHEMBL23551677 0.78 CRBN (0.49) CRBNDDB1IKZF3
SCHEMBL24753401 0.78 CRBN (0.49) CRBNDDB1IKZF3
SCHEMBL23799131 0.76 CRBN (0.42) CRBNDDB1IKZF3
SCHEMBL24406579 0.76 CRBN (0.37) CRBNDDB1IKZF3
SCHEMBL23551390 0.75 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL25091940 0.75 CRBN (0.46) CRBNDDB1IKZF3
SCHEMBL23551370 0.75 CRBN (0.46) CRBNDDB1IKZF3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4119552-A1 REGULATING CHIMERIC ANTIGEN RECEPTORS Dana-Farber Cancer Institute, Inc. (US) 2023-01-18 — — EP disclosed
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