Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 13/20 | 0.70 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.70 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.55 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.55 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.54 |
| ▸ | NCOR2 | Q9Y618 | 7/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2384336 | 1.00 | CRBN (0.70) | CRBNDDB1TNFIL1BTBXA2R | |
| Hydrochloric Acid SCHEMBL2399619 | 0.99 | CRBN (0.69) | CRBNDDB1TNFIL1BTBXA2R | |
| Hydrochloric Acid SCHEMBL2382665 | 0.99 | CRBN (0.69) | CRBNDDB1TNFIL1BTBXA2R | |
| Trifluoroacetic Acid SCHEMBL18448754 | 0.94 | CRBN (0.63) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL2384835 | 0.94 | DDB1 (0.77) | CRBNDDB1TNFIL1BTBXA2R | |
| Hydrochloric Acid SCHEMBL2383396 | 0.93 | DDB1 (0.75) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL3783534 | 0.92 | CRBN (0.72) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL2381344 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL501757 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R | |
| SCHEMBL29808178 | 0.91 | CRBN (0.73) | CRBNDDB1TNFIL1BTBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119552-A1 | REGULATING CHIMERIC ANTIGEN RECEPTORS | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |