Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.68 |
| ▸ | DDB1 | Q16531 | 13/20 | 0.68 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17854848 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL26424353 | 1.00 | CRBN (0.68) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL18379332 | 0.92 | CRBN (0.68) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL17854832 | 0.92 | CRBN (0.73) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL17839575 | 0.91 | CRBN (0.72) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL20188342 | 0.91 | CRBN (0.72) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL17839882 | 0.90 | CRBN (0.68) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL29922205 | 0.90 | CRBN (0.68) | CRBNDDB1HDAC8BRD4ALDH1A1 | |
| SCHEMBL19068584 | 0.88 | CRBN (0.76) | CRBNDDB1ALDH1A1CHRM2OPRM1 | |
| SCHEMBL17854847 | 0.88 | CRBN (0.65) | CRBNDDB1HDAC8BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4119552-A1 | REGULATING CHIMERIC ANTIGEN RECEPTORS | Dana-Farber Cancer Institute, Inc. (US) | 2023-01-18 | — | — | EP | disclosed |