Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23117596 | 0.91 | IDO1 (0.47) | IDO1CRBNDDB1NOS3NOS1 | |
| SCHEMBL23918321 | 0.85 | IDO1 (0.43) | IDO1CRBNDDB1NOS3NOS1 | |
| SCHEMBL23635009 | 0.85 | IDO1 (0.43) | IDO1CRBNDDB1NOS3NOS1 | |
| SCHEMBL23635005 | 0.85 | IDO1 (0.43) | IDO1CRBNDDB1NOS3NOS1 | |
| SCHEMBL24938746 | 0.81 | CRBN (0.53) | IDO1CRBNDDB1 | |
| SCHEMBL23115190 | 0.81 | CRBN (0.52) | CRBNDDB1 | |
| SCHEMBL30922351 | 0.81 | CRBN (0.47) | IDO1CRBNDDB1 | |
| SCHEMBL23115188 | 0.81 | CRBN (0.47) | IDO1CRBNDDB1 | |
| SCHEMBL23115186 | 0.81 | CRBN (0.47) | IDO1CRBNDDB1 | |
| SCHEMBL29323000 | 0.80 | ALDH2 (0.36) | IDO1CRBNDDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001028-A1 | HETEROARYL-3-PIPERIDINEDIONE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-01-26 | — | — | WO | disclosed |