Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1905907 | 1.00 | PTGDR2 (0.48) | PTGDR2NPC1SIGMAR1HTR6MTNR1A | |
| SCHEMBL1905910 | 1.00 | PTGDR2 (0.48) | PTGDR2NPC1SIGMAR1HTR6MTNR1A | |
| SCHEMBL1904524 | 0.94 | PTGDR2 (0.51) | PTGDR2SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL1904521 | 0.94 | PTGDR2 (0.51) | PTGDR2SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL2491410 | 0.93 | PTGDR2 (0.50) | PTGDR2SIGMAR1HTR6 | |
| SCHEMBL2491407 | 0.93 | PTGDR2 (0.50) | PTGDR2SIGMAR1HTR6 | |
| SCHEMBL1902244 | 0.92 | PTGDR2 (0.54) | PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1902243 | 0.92 | PTGDR2 (0.54) | PTGDR2MTNR1AMTNR1B | |
| SCHEMBL1902948 | 0.92 | PTGDR2 (0.49) | PTGDR2SIGMAR1MTNR1AMTNR1B | |
| SCHEMBL1902036 | 0.92 | PTGDR2 (0.49) | PTGDR2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2051962-B1 | (3-AMINO-1,2,3,4-TETRAHYDRO-9H-CARBAZOL-9-YL)-ACETIC ACID DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2011-10-26 | — | — | EP | disclosed |