Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.51 |
| ▸ | MC5R | P33032 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24940027 | 0.87 | MC4R (0.59) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL25586764 | 0.85 | MC4R (0.70) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940865 | 0.85 | MC4R (0.70) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940750 | 0.85 | MC4R (0.60) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL25587829 | 0.83 | MC4R (0.69) | MC4RMC5RMC3RKCNH2HCRTR1 | |
| SCHEMBL25588358 | 0.82 | MC4R (0.53) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL31139165 | 0.81 | MC4R (0.75) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940005 | 0.81 | MC4R (0.75) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24094610 | 0.81 | MC4R (0.75) | MC4RMC5RMC3RKCNH2 | |
| SCHEMBL24940778 | 0.79 | MC4R (0.59) | MC4RMC5RMC3RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019853-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019853-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | MC4R, MC3R, MC5R | MC4R 1/4885MC5R 3/4885MC3R 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.