Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 16/20 | 0.54 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.49 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30105859 | 1.00 | EGFR (0.54) | EGFRALKINSRIGF1R | |
| SCHEMBL24940868 | 0.90 | EGFR (0.57) | EGFRALK | |
| SCHEMBL30105857 | 0.90 | EGFR (0.57) | EGFRALK | |
| SCHEMBL30105883 | 0.89 | EGFR (0.65) | EGFRALKINSRIGF1R | |
| SCHEMBL24940072 | 0.89 | EGFR (0.65) | EGFRALKINSRIGF1R | |
| SCHEMBL24940740 | 0.88 | ALK (0.52) | EGFRALKINSRIGF1R | |
| SCHEMBL30105787 | 0.88 | ALK (0.52) | EGFRALKINSRIGF1R | |
| SCHEMBL24940743 | 0.88 | EGFR (0.58) | EGFRALKINSRIGF1R | |
| SCHEMBL24940070 | 0.88 | EGFR (0.61) | EGFRALKINSRIGF1R | |
| SCHEMBL24940905 | 0.85 | EGFR (0.57) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006088-A1 | COMPOUND FOR EGFR KINASE INHIBITOR, COMPOSITION AND USE THEREOF | 浙江大学智能创新药物研究院 | 2023-02-02 | — | — | WO | disclosed |