Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24940723 | 0.84 | TAF1 (0.30) | — | |
| SCHEMBL24940726 | 0.83 | MC4R (0.33) | HCRTR1HCRTR2PTGDR2 | |
| SCHEMBL24940770 | 0.75 | NAMPT (0.35) | PTGDR2 | |
| SCHEMBL24939965 | 0.71 | MC4R (0.33) | — | |
| SCHEMBL25588015 | 0.71 | MC4R (0.38) | — | |
| SCHEMBL24939971 | 0.68 | HCRTR1 (0.33) | HCRTR1HCRTR2TSPOPTGDR2 | |
| SCHEMBL25586717 | 0.63 | MC4R (0.40) | — | |
| SCHEMBL25586758 | 0.63 | MC4R (0.40) | — | |
| SCHEMBL4253493 | 0.60 | PDE10A (0.45) | — | |
| SCHEMBL18542616 | 0.57 | PDE10A (0.33) | HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230019853-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230019853-A1 | MELANOCORTIN 4 RECEPTOR ANTAGONISTS AND USES THEREOF | MC4R, MC3R, MC5R | HCRTR1 51/4885HCRTR2 61/4885TSPO 2064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.