Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 8/20 | 0.50 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 4/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24942273 | 0.92 | HPGD (0.51) | HPGDMGLLVNN1 | |
| SCHEMBL24942832 | 0.92 | HPGD (0.44) | HPGDMGLLDDR1ROCK2VNN1 | |
| SCHEMBL24942579 | 0.91 | HPGD (0.44) | HPGDMGLLDDR1ROCK2VNN1 | |
| SCHEMBL24942872 | 0.90 | HPGD (0.49) | HPGDMGLLDDR1LRRK2ROCK2 | |
| SCHEMBL24942276 | 0.90 | HPGD (0.43) | HPGDMGLLDDR1 | |
| SCHEMBL24942580 | 0.90 | HPGD (0.53) | HPGDMGLLDDR1LRRK2ROCK2 | |
| SCHEMBL30201664 | 0.89 | HPGD (0.53) | HPGDMGLLDDR1 | |
| SCHEMBL24942912 | 0.89 | HPGD (0.53) | HPGDMGLLDDR1 | |
| SCHEMBL24942254 | 0.89 | HPGD (0.52) | HPGDMGLL | |
| SCHEMBL24942634 | 0.89 | HPGD (0.42) | HPGDMGLLDDR1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009642-A1 | PYRROLO[2,3-B]PYRIDINE PGDH INHIBITORS AND METHODS OF MAKING AND USING | EPIRIUM BIO INC. (US) | 2023-02-02 | — | — | WO | disclosed |