Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.31 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112798 | 1.00 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL30112803 | 1.00 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL30112567 | 0.91 | NT5E (0.40) | NT5ERORCFOLH1NAALAD2MMP14 | |
| SCHEMBL24942508 | 0.91 | NT5E (0.40) | NT5ERORCFOLH1NAALAD2MMP14 | |
| SCHEMBL30112650 | 0.89 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL24942980 | 0.89 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL24942978 | 0.88 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL30112627 | 0.88 | NT5E (0.39) | NT5ERORCFOLH1NAALAD2HPGD | |
| SCHEMBL18526322 | 0.88 | NT5E (0.41) | NT5ERORCMMP14TTRALDH1A1 | |
| SCHEMBL29250145 | 0.87 | NOTUM (0.32) | NOTUMALDH1A1HTTOPRM1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009503-A1 | 2-DIAZO-3-OXO-2,3-DIHYDROSPIRO[INDENE-1,9'-XANTHENE] DERIVATIVES AND SIMILAR COMPOUNDS AS PHOTOACTIVE FLUORESCENT COMPOUNDS FOR PROTEIN LABELING | EIKON THERAPEUTICS INC. (US) | 2023-02-02 | — | — | WO | disclosed |