Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 5/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.44 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.44 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.44 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.44 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.44 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.44 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24945465 | 0.91 | CHRM2 (0.44) | CHRM4GPR119CHRM2CHRM3CHRM1 | |
| SCHEMBL24945737 | 0.91 | CHRM2 (0.48) | CHRM4GPR119CHRM2CHRM3CHRM1 | |
| SCHEMBL24945626 | 0.90 | CHRM2 (0.53) | CHRM4CHRM2CHRM3CHRM1 | |
| SCHEMBL31492265 | 0.87 | CHRM4 (0.44) | CHRM4PRKAA2HDAC3HDAC4HDAC1 | |
| SCHEMBL24945758 | 0.86 | CHRM2 (0.55) | CHRM4CHRM2CHRM3CHRM1 | |
| SCHEMBL23744137 | 0.85 | CHRM2 (0.55) | CHRM4GPR119CHRM2CHRM3CHRM1 | |
| SCHEMBL24945783 | 0.82 | CHRM2 (0.52) | CHRM4CHRM2CHRM3CHRM1 | |
| SCHEMBL24944790 | 0.82 | CHRM2 (0.52) | CHRM4CHRM2CHRM3CHRM1 | |
| SCHEMBL24945612 | 0.82 | CHRM2 (0.52) | CHRM4CHRM2CHRM3CHRM1 | |
| SCHEMBL24945615 | 0.82 | CHRM2 (0.51) | CHRM4CHRM2CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010078-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2023-02-02 | — | — | WO | disclosed |