Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24936177 | 0.95 | CHEK1 (0.67) | CHEK1KCNH2 | |
| SCHEMBL24936318 | 0.91 | CHEK1 (0.55) | CHEK1KCNH2 | |
| SCHEMBL24936180 | 0.89 | CHEK1 (0.70) | CHEK1KCNH2 | |
| SCHEMBL24936296 | 0.88 | CHEK1 (0.72) | CHEK1KCNH2 | |
| SCHEMBL24936186 | 0.88 | CHEK1 (0.66) | CHEK1KCNH2 | |
| SCHEMBL24936295 | 0.88 | CHEK1 (0.66) | CHEK1KCNH2 | |
| SCHEMBL24936199 | 0.88 | CHEK1 (0.71) | CHEK1KCNH2 | |
| SCHEMBL24935497 | 0.86 | CHEK1 (0.72) | CHEK1KCNH2 | |
| SCHEMBL30190446 | 0.86 | CHEK1 (0.57) | CHEK1KCNH2 | |
| SCHEMBL24936163 | 0.85 | CHEK1 (0.68) | CHEK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11564920-B2 | 5-heteroaryl-1H-pyrazol-3-amine derivative | Sumitomo Pharma Co., Ltd. (JP) | 2023-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11564920-B2 | 5-heteroaryl-1H-pyrazol-3-amine derivative | CHEK1, CHEK2, RB1 | CHEK1 1/4885KCNH2 2700/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.