Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 10/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 10/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23744305 | 0.92 | CHRM2 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL23744124 | 0.91 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL23744734 | 0.91 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL24945758 | 0.91 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL23744293 | 0.91 | CHRM4 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL23744286 | 0.91 | CHRM4 (0.66) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL23744688 | 0.91 | CHRM2 (0.55) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL23744687 | 0.90 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL24945664 | 0.90 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3CHRM5 | |
| SCHEMBL26431762 | 0.90 | CHRM4 (0.55) | CHRM2CHRM4CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010078-A1 | MUSCARINIC RECEPTOR 4 ANTAGONISTS AND METHODS OF USE | NEUROCRINE BIOSCIENCES, INC. (US) | 2023-02-02 | — | — | WO | disclosed |