SCHEMBL2494583

SCHEMBL2494583

CCC[C@@H](c1cccc(OCc2ccc(-c3cc(OC)ccc3F)c(O)c2)c1)C(C)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 20/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2500504 1.00 FFAR1 (0.61) FFAR1
SCHEMBL2506429 0.88 FFAR1 (0.62) FFAR1
SCHEMBL2494936 0.88 FFAR1 (0.62) FFAR1
SCHEMBL4271056 0.85 FFAR1 (0.81) FFAR1
SCHEMBL3713755 0.85 FFAR1 (0.81) FFAR1
SCHEMBL4269737 0.83 FFAR1 (0.80) FFAR1
SCHEMBL3712761 0.83 FFAR1 (0.80) FFAR1
SCHEMBL2500503 0.83 FFAR1 (0.70) FFAR1
SCHEMBL2494579 0.83 FFAR1 (0.70) FFAR1
SCHEMBL2503229 0.82 FFAR1 (0.53) FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8030354-B2 2-(5,5-Dimethylcyclopent-1-enyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; metabolic disorders such as type II diabetes AMGEN INC. (US) 2011-10-04 US disclosed