Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30205805 | 1.00 | NAMPT (0.80) | NAMPT | |
| SCHEMBL24946362 | 1.00 | NAMPT (0.80) | NAMPT | |
| SCHEMBL3709532 | 0.89 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3705106 | 0.89 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3702316 | 0.89 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3696943 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3705635 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3700500 | 0.88 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3700082 | 0.86 | NAMPT (1.00) | NAMPT | |
| SCHEMBL3704970 | 0.83 | NAMPT (1.00) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007147-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | THE UNIVERSITY OF MANCHESTER (GB) | 2023-02-02 | — | — | WO | disclosed |