Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLEC | Q15149 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23746045 | 0.88 | CYP2D6 (0.50) | CYP2D6PDK2GABRA1GABRB2KDM4E | |
| SCHEMBL24036971 | 0.80 | ESR1 (0.39) | PDK2L3MBTL1KDM4EMEN1LMNA | |
| SCHEMBL29402623 | 0.78 | MAPT (0.43) | CYP2D6PDK2L3MBTL1KDM4EMEN1 | |
| SCHEMBL11990877 | 0.78 | MAPT (0.43) | CYP2D6PDK2L3MBTL1KDM4EMEN1 | |
| SCHEMBL29450643 | 0.78 | MAPT (0.43) | CYP2D6PDK2L3MBTL1KDM4EMEN1 | |
| SCHEMBL23372320 | 0.77 | PDK2 (0.46) | PDK2L3MBTL1KDM4EMEN1LMNA | |
| SCHEMBL24028010 | 0.77 | PDK2 (0.35) | PDK2L3MBTL1KDM4EMEN1LMNA | |
| SCHEMBL17816904 | 0.77 | MAPT (0.42) | CYP2D6PDK2L3MBTL1KDM4EMEN1 | |
| SCHEMBL30582644 | 0.76 | ESR1 (0.33) | CYP2D6PDK2KDM4EMEN1LMNA | |
| SCHEMBL28603725 | 0.76 | ESR1 (0.33) | CYP2D6PDK2KDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3523834-B1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-01-25 | — | — | EP | disclosed |