SCHEMBL24946649

SCHEMBL24946649

c1ccc(-c2cccc(N(c3ccc(-c4ccc(-n5c6ccccc6c6ccccc65)cc4)cc3)c3ccc(-c4cc5ccccc5c5ccccc45)cc3)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
ATM Q13315 1/20 0.39
CYP11B1 P15538 1/20 0.35
HDAC4 P56524 1/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 3/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
MPI P34949 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR84 Q9NQS5 2/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
TSPO P30536 1/20 0.32
ALOX5 P09917 1/20 0.32
HSD17B10 Q99714 2/20 0.32
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24946652 1.00 KDM4E (0.39) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL21973969 0.96 KDM4E (0.40) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL23822098 0.95 KDM4E (0.37) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL24374293 0.95 KDM4E (0.35) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL24946696 0.95 KDM4E (0.35) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL23821166 0.94 KDM4E (0.39) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL24947146 0.94 KDM4E (0.38) KDM4EL3MBTL1ATMCYP11B1ALDH1A1
SCHEMBL21970819 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL21971541 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMCYP11B1HDAC4
SCHEMBL21973712 0.94 KDM4E (0.44) KDM4EL3MBTL1ATMCYP11B1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed