SCHEMBL24947504

SCHEMBL24947504

c1cc(-c2cccc3ccccc23)cc(N(c2ccc(-c3ccccc3-n3c4ccccc4c4cc5ccccc5cc43)cc2)c2cccc(-c3cccc4ccccc34)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.34
ACMSD Q8TDX5 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CHRNB4 P30926 2/20 0.32
CHRNA3 P32297 2/20 0.32
CHRNA7 P36544 1/20 0.32
PPARG P37231 7/20 0.31
PPARA Q07869 7/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
CHRNA1 P02708 1/20 0.31
CHRNG P07510 1/20 0.31
CHRNB1 P11230 1/20 0.31
CHRNB2 P17787 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
CHRNA4 P43681 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27012087 1.00 MCL1 (0.34) MCL1ACMSDCA12CA1CA2
SCHEMBL24949164 0.98 MCL1 (0.36) MCL1ACMSDCA12CA1CA2
SCHEMBL27012107 0.97 MCL1 (0.36) MCL1ACMSDCA12CA1CA2
SCHEMBL24949196 0.95 MCL1 (0.32) MCL1ACMSDCA12CA1CA2
SCHEMBL24947516 0.95 CA12 (0.35) MCL1ACMSDCA12CA1CA2
SCHEMBL24948478 0.95 MCL1 (0.32) MCL1ACMSDCA12CA1CA2
SCHEMBL24946898 0.94 MCL1 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL27012074 0.94 MCL1 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL24946900 0.94 MCL1 (0.38) MCL1ACMSDCA12CA1CA2
SCHEMBL23154761 0.93 CA12 (0.39) MCL1ACMSDCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023002447-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
WO-2023003403-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed