Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30877544 | 1.00 | NAMPT (0.83) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL164393 | 0.91 | NAMPT (1.00) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30877499 | 0.85 | NAMPT (0.66) | NAMPTALDH1A1MAPTKMT2A | |
| SCHEMBL24948364 | 0.85 | NAMPT (0.66) | NAMPTALDH1A1MAPTKMT2A | |
| SCHEMBL164751 | 0.85 | NAMPT (1.00) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24947635 | 0.84 | NAMPT (0.74) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24946354 | 0.84 | NAMPT (0.67) | NAMPT | |
| SCHEMBL29635804 | 0.83 | NAMPT (1.00) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL24948343 | 0.83 | NAMPT (0.77) | NAMPTMEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL30877520 | 0.83 | NAMPT (0.77) | NAMPTMEN1ALDH1A1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007147-A1 | 6-SUBSTITUTED NAPHTHALENE-1,3-DISULFONIC ACID DERIVATIVES AS MODULATORS OF THE EXTRACELLULAR NICOTINAMIDE PHOSPHORIBOSYL TRANSFERASE (ENAMPT) FOR THE TREATMENT OF E.G. DIABETES | THE UNIVERSITY OF MANCHESTER (GB) | 2023-02-02 | — | — | WO | disclosed |