Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.69 |
| ▸ | HPGD | P15428 | 3/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPY1R | P25929 | 1/20 | 0.51 |
| ▸ | NPY2R | P49146 | 1/20 | 0.51 |
| ▸ | EP300 | Q09472 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | NMT2 | O60551 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31133542 | 1.00 | TSHR (1.00) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL24951457 | 0.89 | TSHR (0.80) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL4165428 | 0.87 | TSHR (0.78) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL27810492 | 0.86 | TSHR (0.76) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL24951555 | 0.85 | TSHR (0.74) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL31133508 | 0.85 | TSHR (0.74) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL14089785 | 0.84 | TSHR (0.72) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL2000858 | 0.83 | TSHR (0.71) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL6824035 | 0.83 | TSHR (0.71) | TSHRKDM4EALDH1A1HPGDMEN1 | |
| SCHEMBL23815706 | 0.82 | KDM4E (1.00) | TSHRKDM4EALDH1A1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007184-A1 | ORGANIC PYRIDINE-PYRAZOLE COMPOUNDS AND THEIR USES | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |