SCHEMBL2495191

SCHEMBL2495191

Clc1csc(Br)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149587 0.73
SCHEMBL12446486 0.73 GFER (0.34)
SCHEMBL67456 0.69
SCHEMBL3833212 0.69
SCHEMBL24963375 0.66
SCHEMBL2427501 0.65
SCHEMBL22812013 0.65
SCHEMBL21737320 0.65
SCHEMBL14127359 0.65
SCHEMBL10762229 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122070275-A Heterocyclic compound and application thereof 成都麻沸散医药科技有限公司 2026-05-19 CN disclosed
US-12410207-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2025-09-09 US disclosed
WO-2025085848-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-04-24 WO disclosed
WO-2025054132-A1 ANTIBACTERIAL COMPOUNDS ARREPATH, INC. (US) 2025-03-13 WO disclosed
WO-2025040546-A1 PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS PROXYGEN GMBH (AT) 2025-02-27 WO disclosed
US-11827666-B2 Galactoside inhibitor of galectins GALECTO BIOTECH AB (DK) 2023-11-28 US disclosed
US-20230348456-A1 QUINAZOLINONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME REPARE THERAPEUTICS INC. (CA) 2023-11-02 US disclosed
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
US-20220402948-A1 EGFR INHIBITOR, COMPOSITION AND PREPARATION METHOD THEREFOR BETTA PHARMACEUTICALS CO., LTD. (CN) 2022-12-22 US disclosed
CN-109563120-B alpha-D-galactoside inhibitors of galectins 格莱克特生物技术公司 2022-12-02 CN disclosed
WO-2015017610-A1 SYK INHIBITORS GILEAD SCIENCES, INC. (US) 2015-02-05 WO disclosed
WO-2014097148-A1 TRICYCLIC COMPOUNDS FOR INHIBITING THE CFTR CHANNEL NOVARTIS AG (CH) 2014-06-26 WO disclosed
WO-2014097147-A1 TRICYCLIC COMPOUNDS AS CFTR INHIBITORS NOVARTIS AG (CH) 2014-06-26 WO disclosed
US-20140171412-A1 TRICYCLIC COMPOUNDS NOVARTIS AG (CH) 2014-06-19 US disclosed
US-20140171417-A1 TRICYCLIC COMPOUNDS NOVARTIS AG (CH) 2014-06-19 US disclosed
US-8030304-B2 Thiazole pyrazolopyrimidines CRF1 receptor antagonists ELI LILLY AND COMPANY (US) 2011-10-04 US disclosed
EP-2094709-B1 THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS LILLY CO ELI (US) 2010-09-15 EP disclosed
US-20100222339-A1 Thiazole pyrazolopyrimidines CRF1 receptor antagonists ELI LILLY AND COMPANY 2010-09-02 US disclosed
EP-2094709-A1 THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2009-09-02 EP disclosed
WO-2008036579-A1 THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS ELI LILLY AND COMPANY (US) 2008-03-27 WO disclosed