Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31106957 | 1.00 | PDE2A (0.41) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL20240254 | 0.80 | PDE2A (0.44) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL31106980 | 0.80 | PDE2A (0.44) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL24954188 | 0.80 | PDE2A (0.44) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL24956772 | 0.74 | MEN1 (0.55) | KMT2AMAPTALDH1A1MEN1HTR2C | |
| SCHEMBL55774 | 0.73 | PDE2A (0.64) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL18343699 | 0.72 | PDE2A (0.49) | PDE2AKMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL24954190 | 0.72 | HRH1 (0.37) | KMT2AMEN1HRH1HRH4 | |
| SCHEMBL31106947 | 0.72 | HRH1 (0.37) | KMT2AMEN1HRH1HRH4 | |
| SCHEMBL30202238 | 0.72 | HRH1 (0.37) | KMT2AMEN1HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |