Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 18/20 | 0.51 |
| ▸ | MTOR | P42345 | 18/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | PDE1A | P54750 | 1/20 | 0.46 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.46 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3985378 | 0.90 | PIK3CA (0.62) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| Hydrochloric Acid SCHEMBL3991341 | 0.89 | PIK3CA (0.61) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL912539 | 0.86 | MTOR (0.55) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL28782188 | 0.85 | PIK3CA (0.54) | PIK3CAMTORPIK3CG | |
| SCHEMBL3986621 | 0.85 | PIK3CA (0.52) | PIK3CAMTORPIK3CG | |
| SCHEMBL30202186 | 0.84 | PDE1C (0.44) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL24955564 | 0.84 | PDE1C (0.44) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL3985904 | 0.84 | PIK3CA (0.74) | PIK3CAMTORPIK3CG | |
| Acetic Acid SCHEMBL27773579 | 0.84 | PIK3CA (0.60) | PIK3CAMTORPIK3CGMAPK14CSNK1G1 | |
| SCHEMBL27773582 | 0.84 | PIK3CA (0.55) | PIK3CAMTORPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |