Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30202121 | 1.00 | CNR2 (0.37) | CNR2SYKLRRK2ADORA1PIK3CA | |
| SCHEMBL24955681 | 0.86 | PIK3CA (0.46) | LRRK2ADORA1PIK3CA | |
| SCHEMBL30202293 | 0.84 | LRRK2 (0.34) | LRRK2ADORA1PIK3CAMAP3K12ADORA3 | |
| SCHEMBL24956765 | 0.84 | LRRK2 (0.34) | LRRK2ADORA1PIK3CAMAP3K12ADORA3 | |
| SCHEMBL30203054 | 0.84 | CNR2 (0.38) | CNR2SYKADORA1PIK3CAMAP3K12 | |
| SCHEMBL24956763 | 0.79 | MTOR (0.49) | LRRK2PIK3CA | |
| SCHEMBL30202095 | 0.79 | MTOR (0.49) | LRRK2PIK3CA | |
| SCHEMBL24954157 | 0.79 | MTOR (0.49) | LRRK2PIK3CA | |
| SCHEMBL30202154 | 0.79 | MTOR (0.49) | LRRK2PIK3CA | |
| SCHEMBL30202224 | 0.77 | PIK3CA (0.37) | CNR2SYKPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007185-A1 | IMIDAZOLE ORGANIC COMPOUNDS AND THEIR USE AGAINST INFLAMMATORY BOWEL DISEASE | Benevolentai Cambridge Limited (GB) | 2023-02-02 | — | — | WO | disclosed |