SCHEMBL24955932

SCHEMBL24955932

Clc1cc2c3cnccc3oc2c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AHR P35869 11/20 0.49
ALDH1A1 P00352 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
DYRK1A Q13627 1/20 0.36
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
RAD52 P43351 1/20 0.35
ACHE P22303 1/20 0.34
PKM P14618 1/20 0.34
TTR P02766 1/20 0.34
HIPK2 Q9H2X6 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24956001 0.89 AHR (0.55) AHRALDH1A1SMN1; SMN2DYRK1AKDM4E
SCHEMBL24958522 0.88 AHR (0.49) AHRALDH1A1DYRK1A
SCHEMBL24958343 0.86 CYP1A2 (0.42) AHRSMN1; SMN2TTR
SCHEMBL24056384 0.82 AHR (0.47) AHRSMN1; SMN2KDM4EPOLBHTT
SCHEMBL24296146 0.81 AHR (0.70) AHRALDH1A1SMN1; SMN2DYRK1AKDM4E
SCHEMBL24910876 0.79 AHR (0.46) AHRALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL24955994 0.76 AHR (0.40) AHRALDH1A1SMN1; SMN2DYRK1AKDM4E
SCHEMBL25500106 0.75 AHR (0.39) AHRALDH1A1SMN1; SMN2KDM4EPOLB
SCHEMBL24958674 0.74 AHR (0.47) AHRALDH1A1SMN1; SMN2DYRK1AKDM4E
SCHEMBL431566 0.74 KDM4E (0.46) AHRALDH1A1SMN1; SMN2KDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287252-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-01-19 WO disclosed