SCHEMBL24955997

SCHEMBL24955997

Clc1cnc2oc3c4ccccc4ccc3c2c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 13/20 0.45
CYP1A2 P05177 13/20 0.45
CYP1B1 Q16678 13/20 0.45
KDM4E B2RXH2 4/20 0.41
MAPT P10636 3/20 0.41
ALDH1A1 P00352 3/20 0.41
HPGD P15428 3/20 0.41
HTT P42858 2/20 0.41
PAX8 Q06710 1/20 0.41
KMT2A Q03164 2/20 0.41
PRKDC P78527 2/20 0.39
HSD17B10 Q99714 2/20 0.39
ALOX15 P16050 1/20 0.39
PDE5A O76074 1/20 0.39
TP53 P04637 1/20 0.39
ABCB1 P08183 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP19A1 P11511 1/20 0.39
CYP2C9 P11712 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25493076 0.79 AHR (0.41) CYP1A1CYP1A2MAPTPAX8KMT2A
SCHEMBL24958331 0.78 CYP1A1 (0.44) CYP1A1CYP1A2CYP1B1KDM4EMAPT
SCHEMBL24637049 0.77 NR4A2 (0.45) CYP1A1CYP1A2CYP1B1KDM4EMAPT
SCHEMBL20696169 0.76 CYP1A1 (0.42) CYP1A1CYP1A2CYP1B1KDM4EMAPT
SCHEMBL15631660 0.76 AHR (0.50) KDM4EMAPTALDH1A1HPGDKMT2A
SCHEMBL24959863 0.76 CYP1A1 (0.47) CYP1A1CYP1A2CYP1B1KDM4EMAPT
SCHEMBL24911590 0.75 IDO1 (0.39) KDM4EMAPTPRKDCTP53TSHR
SCHEMBL24958225 0.74 NR4A2 (0.45) CYP1A1CYP1A2CYP1B1KDM4EALDH1A1
SCHEMBL22019096 0.73 AHR (0.58) CYP1A1CYP1A2CYP1B1KDM4EMAPT
SCHEMBL29739116 0.73 AHR (0.58) CYP1A1CYP1A2CYP1B1KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023287252-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2023-01-19 WO disclosed