⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252479 | 0.70 | — | — | |
| SCHEMBL10039293 | 0.66 | TDP1 (0.43) | — | |
| SCHEMBL14445080 | 0.66 | — | — | |
| SCHEMBL13952255 | 0.63 | — | — | |
| SCHEMBL4607701 | 0.61 | — | — | |
| SCHEMBL4742487 | 0.58 | — | — | |
| SCHEMBL11372614 | 0.58 | — | — | |
| SCHEMBL24348140 | 0.58 | — | — | |
| SCHEMBL21737259 | 0.58 | — | — | |
| Propionamide SCHEMBL29428871 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230021705-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. | 2023-01-26 | — | — | US | disclosed |