Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CBX7 | O95931 | 2/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.40 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | MMP13 | P45452 | 2/20 | 0.38 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.38 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.38 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5675323 | 0.89 | CBX7 (0.47) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2496818 | 0.86 | KMT2A (0.42) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2498534 | 0.84 | CBX7 (0.39) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL5677735 | 0.83 | KMT2A (0.44) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2499409 | 0.82 | CBX7 (0.38) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2495320 | 0.82 | KMT2A (0.42) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2497477 | 0.82 | KMT2A (0.42) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2492996 | 0.82 | KMT2A (0.42) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2496408 | 0.81 | CBX7 (0.40) | KMT2ACBX7CDYLIDO1ADCY8 | |
| SCHEMBL2492829 | 0.81 | KMT2A (0.40) | KMT2ACBX7CDYLIDO1ADCY8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |