SCHEMBL249642

SCHEMBL249642

CC[C]1NCCN1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469800 0.73
Propane SCHEMBL28568051 0.62 MEN1 (0.39)
Butane SCHEMBL4969720 0.60 KMT2A (0.38)
SCHEMBL4922604 0.60
Alcohol SCHEMBL22733479 0.58 KMT2A (0.41)
SCHEMBL14154751 0.57
SCHEMBL249133 0.56
SCHEMBL13228788 0.56
SCHEMBL19269020 0.54 CRBN (0.33)
SCHEMBL17036823 0.54 CRBN (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050197338-A1 Substituted pyrazole urea compounds for the treatment of inflammation PHARMACIA AND UPJOHN COMPANY LLC 2005-09-08 US claimed
WO-2005037797-A1 SUBSTITUTED PYRAZOLE UREA COMPOUNDS FOR THE TREATMENT OF INFLAMMATION PHARMACIA CORPORATION (US) 2005-04-28 WO claimed
EP-4281490-A1 STORAGE-STABLE 1K SPRAY ADHESIVES BASED ON POLYURETHANE DISPERSIONS Covestro Deutschland AG (DE) 2023-11-29 EP disclosed
EP-3856814-B1 DISPERSION ADHESIVESTITLE COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) 2023-06-14 EP disclosed
EP-3545025-B1 METHOD FOR PRODUCING AN AT LEAST PARTIALLY COATED OBJECT COVESTRO DEUTSCHLAND AG (DE) 2022-10-12 EP disclosed
EP-3818091-A1 METHOD AND APPARATUS FOR PRODUCING A POLYURETHANE DISPERSION HAVING REDUCED FOAM FORMATION Covestro Intellectual Property GmbH & Co. KG (DE) 2021-05-12 EP disclosed
US-10752727-B1 Process and apparatus for continuous production of aqueous polyurethane dispersions COVESTRO DEUTSCHLAND AG (DE) 2020-08-25 US disclosed
WO-2020007756-A1 METHOD AND APPARATUS FOR PRODUCING A POLYURETHANE DISPERSION HAVING REDUCED FOAM FORMATION COVESTRO DEUTSCHLAND AG (DE) 2020-01-09 WO disclosed
EP-3320005-A1 PROCESS AND APPARATUS FOR CONTINUOUS PRODUCTION OF AQUEOUS POLYURETHANE DISPERSIONS Covestro Deutschland AG (DE) 2018-05-16 EP disclosed
WO-2017009161-A1 PROCESS AND APPARATUS FOR CONTINUOUS PRODUCTION OF AQUEOUS POLYURETHANE DISPERSIONS COVESTRO DEUTSCHLAND AG (DE) 2017-01-19 WO disclosed
WO-2015077376-A1 IMPROVED MODIFIED SAND SPORTS SURFACES EQUESTRIAN SURFACES, INC. (US) 2015-05-28 WO disclosed
US-5747582-A POLYETHERURETHANES FOR COATINGS BAYER AKTIENGESELLSCHAFT (DE) 1998-05-05 US disclosed
US-5716676-A Aqueous coating compositions and their use for the preparation of coatings that are permeable to water vapor BAYER AKTIENGESELLSCHAFT (DE) 1998-02-10 US disclosed
US-4218571-A HYDROGENATION CATALYST MADE BY HYDROLYSIS AND POLYMERIZATION OF SILANE COMPOUND FOLLOWED BY ROASTING MOBIL OIL CORPORATION (US) 1980-08-19 US disclosed
US-4176161-A Oxidation over synthetic amorphous silicas MOBIL OIL CORPORATION (US) 1979-11-27 US disclosed
US-4174356-A CATALYST OR SUPPORT MOBIL OIL CORPORATION (US) 1979-11-13 US disclosed
US-4086261-A Methanation over synthetic amorphous silicas MOBIL OIL CORPORATION (US) 1978-04-25 US disclosed
US-4056488-A SYNTHETIC AMORPHOUS SILICAS OF PREDETERMINED PORE DISTRIBUTION, METHOD OF PRODUCING SAME MOBIL OIL CORPORATION (US) 1977-11-01 US disclosed
US-4003825-A CRACKING CATALYSTS MOBIL OIL CORPORATION (US) 1977-01-18 US disclosed
US-3983055-A Synthetic amorphous silicas of predetermined pore distribution method of producing same MOBIL OIL CORPORATION (US) 1976-09-28 US disclosed