Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ST6GAL1 | P15907 | 7/20 | 0.52 |
| ▸ | ST3GAL1 | Q11201 | 2/20 | 0.52 |
| ▸ | ST3GAL3 | Q11203 | 1/20 | 0.51 |
| ▸ | FNTA | P49354 | 2/20 | 0.45 |
| ▸ | FNTB | P49356 | 2/20 | 0.45 |
| ▸ | SRD5A1 | P18405 | 7/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ATIC | P31939 | 1/20 | 0.39 |
| ▸ | CDC25A | P30304 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1310798 | 0.78 | FNTA (0.53) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL16505506 | 0.71 | FNTA (0.45) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL1310805 | 0.71 | FNTA (0.45) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL13262135 | 0.71 | FNTA (0.45) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL12115312 | 0.71 | FNTA (0.45) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL1310949 | 0.70 | ST6GAL1 (0.43) | ST6GAL1ST3GAL1ST3GAL3FNTAFNTB | |
| SCHEMBL2448736 | 0.69 | NPC1L1 (0.55) | ST6GAL1ST3GAL1ST3GAL3USP2ATIC | |
| SCHEMBL20480236 | 0.69 | ST6GAL1 (0.75) | ST6GAL1ST3GAL1ST3GAL3USP2 | |
| SCHEMBL20480234 | 0.69 | ST6GAL1 (0.75) | ST6GAL1ST3GAL1ST3GAL3USP2 | |
| SCHEMBL1311793 | 0.69 | FNTA (0.81) | FNTAFNTBSRD5A1SRD5A2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370071-A1 | NOVEL OXIME DERIVATIVES OF 3,5-SECO-4-NOR-CHOLESTANE, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PREPARING SAME | Trophos (FR) | 2011-10-05 | — | — | EP | disclosed |
| WO-2010076418-A1 | NOVEL OXIME DERIVATIVES OF 3,5-SECO-4-NOR-CHOLESTANE, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND METHOD FOR PREPARING SAME | TROPHOS (FR) | 2010-07-08 | — | — | WO | disclosed |