SCHEMBL2496599

SCHEMBL2496599

CN(CCCCC(NC(=O)CCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)C(=O)O)Cc1nccn1CC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 20/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22984221 0.91 FOLH1 (0.47) FOLH1
SCHEMBL23553141 0.91 FOLH1 (0.47) FOLH1
SCHEMBL29521873 0.91 FOLH1 (0.47) FOLH1
SCHEMBL15335284 0.91 FOLH1 (0.47) FOLH1
SCHEMBL1740716 0.90 FOLH1 (0.49) FOLH1
SCHEMBL1740395 0.87 FOLH1 (0.50) FOLH1
SCHEMBL1740406 0.87 FOLH1 (0.50) FOLH1
SCHEMBL20180890 0.85 FOLH1 (0.42) FOLH1
SCHEMBL22647083 0.85 FOLH1 (0.43) FOLH1
SCHEMBL16254533 0.85 FOLH1 (0.44) FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2373621-A2 TECHNETIUM-AND RHENIUM-BIS(HETEROARYL)COMPLEXES AND METHODS OF USE THEREOF Molecular Insight Pharmaceuticals, Inc. (US) 2011-10-12 EP disclosed
WO-2010065899-A2 TECHNETIUM-AND RHENIUM-BIS(HETEROARYL)COMPLEXES AND METHODS OF USE THEREOF MOLECULAR INSIGHT PHARMACEUTICALS, INC. (US) 2010-06-10 WO disclosed