Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.74 |
| ▸ | LMNA | P02545 | 6/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.74 |
| ▸ | SHBG | P04278 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.74 |
| ▸ | SERPINA6 | P08185 | 3/20 | 0.74 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.74 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.74 |
| ▸ | TSHR | P16473 | 3/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.74 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.64 |
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.64 |
| ▸ | HTR2B | P41595 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24966600 | 1.00 | AR (0.80) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL21231430 | 1.00 | AR (0.80) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL22872790 | 0.92 | AR (0.77) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL11813295 | 0.91 | AR (0.82) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL6565022 | 0.91 | AR (0.82) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL21340509 | 0.91 | AR (0.76) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL11410908 | 0.90 | AR (0.75) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL23265222 | 0.90 | AR (0.75) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| SCHEMBL21340634 | 0.90 | AR (0.75) | ARSMN1; SMN2LMNAHSD17B10SHBG | |
| Clascoterone SCHEMBL24358737 | 0.89 | AR (1.00) | ARSMN1; SMN2LMNAHSD17B10SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001223-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |